Intra-articular urokinase in rheumatoid arthritis.
نویسندگان
چکیده
منابع مشابه
Intra-articular urokinase in rheumatoid arthritis.
It has been suggested that urokinase may have some value in the management of patients with rheumatoid arthritis (Morotomi and Tatezawa, 1970; Ito and Naito, 1970). This fibrinolytic agent activates plasminogen, converting it to plasmin competitively and reversibly. Thus there is some basis, however speculative, for its use in rheumatoid arthritis-a disease which on several clinical and laborat...
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The past 10 years have witnessed an increased interest in the plasminogen activation system and its potential role(s) in rheumatoid arthritis (RA). Two types of plasminogen activators (PAs), urokinase (uPA) and tissue type PA (tPA), which are structurally, immunologically, and genetically distinct, have been identified in mammals. Both PAs are secreted as a single chain protein, which in the ca...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1974
ISSN: 0003-4967
DOI: 10.1136/ard.33.2.124